Six young hopefuls at the Hot Wheels Ultimate Garage Racing Camp learn the skills they need to become the next generation of amazing racers.

In 2062, two decades after the failure of a massive workforce automation project. However, Artemis, the artificial intelligence at the core of that project, had decided to attack humanity, and the resulting war laid waste to Earth.

Puberty Syndrome—a rumored, mysterious syndrome that only affects those in their puberty. For example, a bunny girl suddenly appeared in front of Sakuta Azusagawa. The bunny girl's real identity is Mai Sakurajima, a teenage celebrity who is currently an inactive high school senior. For some reason, her charming figure does not reflect in the eyes of others. In the course of revealing the mystery behind this phenomenon, Sakuta begins to explore his feelings towards Mai. Set in a city where the skies and seas shine, Sakuta unfolds the meaning behind his bizarre encounters on women with the said syndrome.